Cognitive & Mood

Adamax Adamax is a modified version of Semax sold as a nootropic research compound. It has no published research of its own, and the suppliers who sell it do not agree on what molecule it actually is. Here is what we could verify. View research notes → Dihexa Dihexa is a synthetic angiotensin IV derivative sold as a nootropic on the research market. The two papers that established how it was supposed to work were retracted in April 2025 for falsified or fabricated data, and the market has largely carried on as though nothing happened. View research notes → DSIP A nonapeptide isolated in 1977 and named for the sleep stage it was expected to induce. The controlled human work that followed did not find that effect, and the name has outlived the finding. View research notes → Na-Semax / Na-Selank Blend A pre-mixed combination of the sodium-salt forms of two Russian-developed heptapeptides — Semax for cognition and neuroprotection, Selank for anxiety — sold together as a single vial. The combined blend product has no current vendor; both compounds remain available individually elsewhere on this site. View research notes → NAD+ One of the most-studied molecules in longevity science. NAD+ is a coenzyme rather than a peptide, but is widely tracked alongside research peptides for its role in aging, cellular repair, and metabolic function. View research notes → NAD+ vs. 5-Amino-1MQ, which one you actually want Both get sold in the energy aisle and they do almost nothing alike. One is a molecule you're running low on, the other blocks an enzyme that gets in the way, and that difference decides whether you take it every week or a few months a year. Read → Oxytocin A nine-amino-acid hormone made in the hypothalamus, best known as an approved obstetric drug and, separately, as the subject of two decades of intranasal human research that found far less than the popular 'bonding hormone' story claims. No vendor in our tracked set currently lists it. View research notes → Pinealon A short synthetic peptide (Glu-Asp-Arg) studied mostly in animal and cell models for neuroprotection, antioxidant activity, and brain aging. Here's what the research actually shows, plus what it tends to cost per mg. View research notes → Selank Selank is a synthetic heptapeptide studied primarily for anxiolytic and cognitive effects. It is approved as a nasal spray in Russia and has one published human clinical trial. Here is what the evidence shows. View research notes → Semax Semax is a synthetic ACTH-derived heptapeptide studied primarily for neuroprotection and cognitive effects. It has regulatory approval in Russia and a growing body of mechanistic research. Here is what the evidence looks like. View research notes → Tesamorelin Tesamorelin is a synthetic GHRH analog FDA-approved as Egrifta for excess visceral fat in people with HIV. Researchers also study it for liver fat reduction, metabolic health, and potential cognitive effects in populations with growth hormone dysregulation. View research notes → The FDA's Next Peptide Hearing Includes One Whose Key Papers Were Retracted A second compounding hearing is set for before the end of February 2027, and five peptides are on the slate. Three of them are compounds our readers already buy, and one is dihexa acetate, whose two foundational papers were retracted last year for fabricated data. Read → VIP (Vasoactive Intestinal Peptide) VIP is a twenty-eight amino acid peptide the body makes on its own, isolated from gut tissue in 1970. Its synthetic form is called aviptadil, and it has more real clinical trial data behind it than most research peptides. Nearly all of that data comes from routes and conditions that have nothing to do with what people buy it for. View research notes →