VIP dosage chart by route

The injected rows are what vendors describe, and the nasal and hospital rows are different products, so read across each row before comparing amounts. VIP is also sold as aviptadil, its drug name, and the hospital trials use that word. Background on the peptide and the trial record is on the VIP page.

Research VIP is sold as a freeze-dried powder. Across the vendors we track it's listed most often in 10 mg vials, then 5 mg, with a few 6 mg. You mix it with bacteriostatic water, which is sterile water with a preservative so one vial can be drawn from more than once. The tables show units on a U-100 syringe, which holds 100 units in 1 mL, for 1, 2 and 3 mL of water. The amounts are 50 mcg, the most common, and 100 and 200 mcg from the higher version.

Units are math from the chart amounts, with strength rounded to the nearest whole number.

The draws are tiny at these amounts, so more water makes them easier to read. On a 10 mg vial the 50 mcg draw stays under 2 units even with 3 mL, which is why a 5 mg vial suits the most common amount better. For any other vial, water or amount, the reconstitution calculator does the same math.

VIP nasal spray dosage

The nasal spray is a compounded prescription product, made by a pharmacy at 50 mcg per 0.1 mL spray, so each spray is a fixed dose and there's no mixing math. The common pattern in protocol write-ups is one spray four times a day, which is 200 mcg a day. We don't give math for turning a research vial into a spray, because the pharmacy's metering and sterility are what the prescription product is.

Twice a day for the injected version. Vendors describe a morning and an evening dose, 50 mcg each. The higher version is once or twice a day.

Eight weeks is the convention. Vendor pages describe 8 weeks on and a similar break, and no study or label sets a length. The CIRS protocol runs the spray for months.

Under the skin. Vendor pages describe the belly or outer thigh, with the spot rotated. No study or label sets a time of day.

For planning, 100 mcg a day for 8 weeks is 5.6 mg in all. Compare vendors on price per milligram against a total like that, not on the price of one vial.

A mixed vial goes on a 28-day clock in the fridge the day water goes in, however much of it gets used. A 5 mg vial at 100 mcg a day holds 50 days of VIP, but the mixed vial expires at day 28, so about 2.2 mg goes unused, and a 10 mg vial at that amount leaves about 7.2 mg. At 200 mcg a day a 5 mg vial lasts 25 days. At 200 mcg twice a day it gives 12 full days with one dose left over, and a 10 mg vial gives 25 days.

Eight weeks at 100 mcg a day is 5.6 mg, but the 28-day clock means it takes two vials mixed one after the other, whichever size you buy. At that amount a 10 mg vial goes mostly unused, so price the 5 mg vials against the 10 mg ones on what you'll actually use.

The pairing people describe is VIP with thymosin alpha-1, each on its own schedule over the same weeks, because both come up for immune complaints. No study tests the two together. Thymosin alpha-1 is twice a week and VIP is twice a day, so they're separate injections, and each has its own amounts on its own dosage chart.

These are reported experiences from people who run VIP, plus what the molecule is known to do, not findings from a study of the injected vial.

Flushing, warmth or light-headedness when you stand. VIP was first described in 1970 as a strong blood vessel widener, so this is expected. People describe sitting for a few minutes after a dose.

Headache or loose stools around dosing. Reported less often. People usually see whether it settles within the first week or two.

Low blood pressure or blood pressure medicine. Because of that widening effect, people who already run low or take medicine that lowers blood pressure are the ones who report watching most closely for light-headedness.

The hospital trials ran 3 days in a drip or 4 weeks in a nebulizer, in patients very different from someone injecting at home, so their safety results don't tell you much about months under the skin. The open questions are laid out on the VIP page.