Semax dosage chart by route

Most of what people do with semax, the morning dose, the dose before a work block, the short course and the break, is reported use, and the injected rows are vendor and community convention. The last two rows are what the studies were for, an approved nasal-drop course and a hospital use after stroke. Each row names its source, so you can see which is which. Background on the compound lives on the Semax page.

Semax is sold as freeze-dried powder, in 5 mg and 10 mg vials. You mix it with bacteriostatic water, which is sterile water with a preservative so one vial can be drawn from more than once. The table shows the units to draw on a U-100 syringe, which holds 100 units in 1 mL, for 1, 2 and 3 mL of water.

A 5 mg vial doubles each number at the same water, so 2 mL gives 12 units for 300 mcg and 24 units for 600 mcg. More water makes each draw bigger and easier to measure.

For any other vial, water or amount, the reconstitution calculator does the same math.

Semax nasal spray dosage

Ready-made research sprays are sold by the total milligrams in the bottle, and the amount per spray is rarely on the listing. The formula is milligrams divided by the number of sprays, and many pumps give about 0.1 mL a spray, which is our working assumption, so about 10 sprays per mL, and the bottle's own pump may differ. For scale, one drop of the approved 0.1% solution is 50 mcg.

The same 30 mg in a bigger bottle is nearly four times weaker per spray. If a listing doesn't give the fill volume, ask the vendor before buying. Spray counts assume a 0.1 mL pump, a common size and not a figure from any listing, so a bottle's own pump changes them. Bottle sizes here are examples of the math, not a list of what's sold.

Before the work you want covered. People report taking semax in the morning, or 15 to 30 minutes before a focused stretch such as a work block, a shift or a study session, and often only on the days they want it. The effect is described as largely gone within a few hours, and some people split the day's amount in two, morning and early afternoon, instead of taking it all at once.

As needed, or in short courses. Both are common. The nasal spray is the form people describe most for as-needed days, and injected vials more often run as a course of up to 14 days with one to three weeks off. The reason people give is that the effect is commonly reported to fade after 2 to 3 weeks of daily use, so they space it out to keep it working. The question about a break below has more.

Mornings. Vendors and the community say once a day in the morning, and the split pattern stops by early afternoon, because people report later doses cut into sleep. No study tests the timing.

What the label was for. The label says 2 to 3 drops per nostril at a time, repeated through the day to reach the daily amount, and for optic nerve disease it adds 2 to 3 times a day. That's a daily course of 3 to 5 days, extended to 14, for a diagnosed condition. The injected patterns borrow the course, and nobody has tested the injected version. The label doesn't say whether to repeat a course or how long to wait.

A mixed vial goes on a 28-day clock in the fridge the day water goes in, however much of it gets used.

A 10 mg vial at 600 mcg a day lasts 16 days, and at 300 mcg a day it would last 33 but expires at 28 with about 1.6 mg unused. A 5 mg vial lasts 16 days at 300 mcg and 8 days at 600 mcg. A 14-day course takes 4.2 mg at 300 mcg a day or 8.4 mg at 600 mcg, so a 5 mg vial fits the lower amount and a 10 mg vial fits the higher one.

The pairing people report most is semax with selank, semax in the morning and selank later, reported as calm but alert, and our Semax vs Selank comparison sets them side by side. Both were developed in Russia, and no study tests them together. Each has its own amounts on its own dosage chart.

These are reported experiences, not findings from a study of research vials.

Feeling wired or restless. People report it, especially with larger amounts or later doses, and they usually drop the amount or take it earlier. The Russian label lists only mild nasal irritation with long use, so this one rests on user reports alone.

Trouble sleeping. People report it after afternoon or evening doses and move the dose to the morning.

Irritation in the nose. The Russian label lists mild irritation of the nose with long use, and people report it with sprays and stop or dilute.

The effect fading. People report that semax weakens after a couple of weeks of daily use, and they take a break or move to as-needed use.

Nothing after 14 days. A minority feel nothing at all, and people who notice no change by the end of a course often stop and reassess, and that's reported experience.