DSIP dosage chart for injection

The amount vendor pages give for DSIP is 100 to 200 mcg a night under the skin, 30 to 60 minutes before bed. The human studies we found gave it into a vein instead.

Reviewed October 9, 2026 6 min read

How much DSIP do people take?

The amount most often given for DSIP is 100 to 200 mcg a night, injected under the skin 30 to 60 minutes before bed, for two to four weeks at a time. That comes from vendor education pages, with no named clinician or study behind it. The human studies we found gave 25 nanomoles per kg of body weight into a vein on three or four nights, which works out to about 1.4 mg for a 150 pound adult.

Amount

100–200 mcga night, up to 500 in the higher pattern

Timing

Before bed30 to 60 minutes

Course

2–4 weeksthen a break

Route

Under the skininjection

Amount, timing, course and route are the convention on vendor education pages, with no named clinician or study behind them. No label sets any of them, and the human studies we found gave DSIP into a vein, not under the skin.

DSIP dosage chart

Most common 100–200 mcgOnce a night, 30 to 60 minutes before bed, for 2 to 4 weeks Vendor education pages, repeated with no named clinician or study behind the amount or the timing

Higher Up to 500 mcgOnce a night Vendor education pages. Nothing shows a higher amount works better

Human sleep studies 25 nmol per kg of body weight (about 1.4 mg for 150 pounds)Once a day for 3 or 4 nights, into a vein Two sleep-lab studies in people with long-term insomnia, in 1987 and 1992. Not an under-the-skin amount, and we converted the unit to milligrams. The improvements were small

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How to read the DSIP chart

The first two rows are convention from vendor pages, so read the source column before comparing amounts. The last row is the only human dosing we found. It was given into a vein and by body weight, so it can't be read across to an injection under the skin. Background on what DSIP is lives on the DSIP page.

A South Asian woman in her late forties sitting on the edge of her bed in bright morning light, stretching and smiling after a good night's sleep

DSIP injection dosage and mixing

DSIP is sold as a freeze-dried powder for injection under the skin, and the vial sizes we've seen listed are 2 mg, 5 mg and 10 mg. You mix it with bacteriostatic water, which is sterile water with a preservative so one vial can be drawn from more than once. The tables cover 2 mg and 5 mg vials and show the units to draw on a U-100 syringe, which holds 100 units in 1 mL, for 1, 2 and 3 mL of water.

5 mg vial of DSIP, units on a U-100 syringe
Water	Strength	100 mcg	200 mcg	500 mcg
1 mL	5,000 mcg per mL	2 units	4 units	10 units
2 mL	2,500 mcg per mL	4 units	8 units	20 units
3 mL	about 1,667 mcg per mL	6 units	12 units	30 units

2 mg vial of DSIP, units on a U-100 syringe
Water	Strength	100 mcg	200 mcg	500 mcg
1 mL	2,000 mcg per mL	5 units	10 units	25 units
2 mL	1,000 mcg per mL	10 units	20 units	50 units
3 mL	about 667 mcg per mL	15 units	30 units	75 units

A few units is hard to read on a syringe. More water makes each draw bigger and easier to measure, so 2 or 3 mL is the easier choice for a 5 mg vial, and 3 mL gives 3 units for 100 mcg from a 10 mg vial.

For any other vial, water or amount, the reconstitution calculator does the same math.

When and how often

Once a night, 30 to 60 minutes before bed. That's the timing on vendor pages, and we found nothing published that tests it. The 1992 human study gave it in the afternoon before each recorded night.

Two to four weeks, then a break. Short blocks with a break after are the course described most often, and we couldn't find where the length or the break came from.

The human studies dosed by body weight, 25 nanomoles per kg of body weight. Converted, that's about 21 mcg per kg, or 9.6 mcg per pound, so about 1.4 mg for a 150 pound adult and 1.7 mg for 180 pounds. It was given into a vein, so it can't be read across to an injection under the skin.

How long a vial lasts

A mixed vial goes on a 28-day clock in the fridge the day water goes in, however much of it gets used. At 100 mcg a night, a 5 mg vial holds 50 doses but only 28 fit inside the clock, so about 2.2 mg expires. At 200 mcg it's 25 nights, three short of a 4-week stretch, and a 2 mg vial lasts 20 nights at 100 mcg.

For planning, a 4-week stretch is 2.8 mg at 100 mcg a night and 5.6 mg at 200 mcg. Compare vendors on price per milligram against the total you'll use, and keep in mind that the vial you can afford may be bigger than the one you can finish.

Signs the amount or timing is off

These are reported experiences, not findings from a study of research vials.

Groggy or hungover in the morning. People report feeling groggy or hungover in the morning, and they usually drop to a smaller amount or stop.

Vivid or disrupted dreams. People report it, and some move the dose earlier in the evening or stop.

Headaches. People report them, and if they carry on past a few days people usually stop.

Nothing after two to four weeks. People often stop here rather than raising the amount. We found no human study of an injection under the skin to say what to expect, so some people set the stretch and the decision in advance.

It's sold for research, and the human work on DSIP is small and old. You knew that, it's why you're reading this and not the label.

Questions people ask about DSIP dosage

How much DSIP should I take at night?

Vendor pages most often give 100 to 200 mcg under the skin, 30 to 60 minutes before bed, with some going up to 500 mcg. No label or study sets an injected amount, so treat it as convention.

How much bacteriostatic water for a 5 mg vial of DSIP?

You can use 1, 2 or 3 mL, because the water only changes the size of each draw. With 2 mL, 100 mcg is 4 units on a U-100 syringe and 200 mcg is 8 units.

Can you take DSIP every night, or only when you need it?

No study or label sets either. Vendor pages describe nightly use, and some people describe five nights on and two off to stretch a vial, which is community habit. We found no study of as-needed use, so there's nothing to say about how it would compare.

Which DSIP vial size should I buy?

At 100 mcg a night a 5 mg vial holds 50 doses but only 28 fit inside the mixed vial's 28 days, so about 2.2 mg expires. A 2 mg vial lasts 20 nights at that amount, so a 4-week stretch needs a second one.

Has DSIP been tested in people?

Yes, in small sleep-lab studies in 1987 and 1992, with the peptide given into a vein. Total sleep time rose through the lighter stage in the first, and the authors called the gain of little clinical significance. The second found weak effects and concluded it was not likely to be of major benefit.

Is there a DSIP nasal spray dosage?

We found no study of a nasal spray, and no label. The amounts on this page are for injection under the skin and can't be carried over to a spray.

Where to buy DSIP

The five lowest per-mg prices in this morning's check, one listing per vendor.

IDUN Peptides 10 mg · $29.99 $3.00/mg
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Double R Labs 15 mg · $44.99 $3.00/mg
High confidence Code PPL · 15% off Our review
Alpha Labs 10 mg · $31.49 $3.15/mg
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KAM Research Solutions 10 mg · $35.10 $3.51/mg
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Superior Labs Research 15 mg · $55.00 $3.67/mg
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