Sleep
Research notes tagged Sleep.
CJC-1295
CJC-1295 is a long-acting synthetic analog of growth hormone-releasing hormone (GHRH), engineered to bind albumin and extend its half-life from minutes to roughly a week. Here is what the human and animal research actually shows.
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CJC-1295 (with DAC) + Ipamorelin
Two peptides that target different points in the growth hormone axis are frequently studied in combination. This page covers what the research actually shows for each.
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CJC-1295 No DAC + Ipamorelin
CJC-1295 No DAC and Ipamorelin are studied in combination because they activate two different receptor systems in the growth hormone axis, producing additive GH pulses through independent pathways. This page covers what the research shows.
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DSIP
A nonapeptide isolated in 1977 and named for the sleep stage it was expected to induce. The controlled human work that followed did not find that effect, and the name has outlived the finding.
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Epithalon
Epithalon is the most-studied synthetic tetrapeptide in longevity research. The evidence centers on telomere biology and pineal gland function. Here is what the published literature actually shows.
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GHRP-2
GHRP-2 is a synthetic hexapeptide that acts as a potent ghrelin receptor agonist, stimulating growth hormone release from the pituitary. Researchers study it for GH axis activation, diagnostic testing, and the physiological effects of ghrelin pathway stimulation.
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GHRP-6
The original growth hormone releasing peptide, developed in 1984. Researchers studying the GH axis often compare GHRP-6 with its successors as a reference compound.
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Ipamorelin
Ipamorelin is a selective growth hormone secretagogue studied for its ability to stimulate GH release without significant effects on cortisol or prolactin. Here is a look at the current research.
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Pinealon
A short synthetic peptide (Glu-Asp-Arg) studied mostly in animal and cell models for neuroprotection, antioxidant activity, and brain aging. Here's what the research actually shows, plus what it tends to cost per mg.
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Sermorelin
Sermorelin is a synthetic fragment of growth hormone-releasing hormone studied for its ability to stimulate endogenous GH secretion. Researchers have examined its use in growth hormone deficiency, body composition, and age-related hormonal decline.
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Tesamorelin
Tesamorelin is a synthetic GHRH analog FDA-approved as Egrifta for excess visceral fat in people with HIV. Researchers also study it for liver fat reduction, metabolic health, and potential cognitive effects in populations with growth hormone dysregulation.
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