Sermorelin dosage chart for nightly use

Four patterns are on the chart, and they don't describe the same thing. The first is what vendors describe for adults. The other three are amounts from published work. The adult study and the children's treatment are both higher than the vendor range, and the diagnostic test is a single clinic dose that is lower, so read across each row before you compare amounts. Background on the peptide, including its history as a children's drug, is on the sermorelin page.

Sermorelin is sold as a freeze-dried powder, most often in 5 mg and 10 mg vials, with 2 mg vials much less common. You mix it with bacteriostatic water, which is sterile water with a preservative so one vial can be drawn from more than once.

The tables show units on a U-100 syringe, which holds 100 units in 1 mL, for 1, 2 and 3 mL of water. The amounts are the two ends of the vendor range, 200 and 300 mcg.

Units are math from the chart amounts, with strength rounded to the nearest whole number. More water makes each draw bigger and easier to read.

The small draws are the practical point. At 2 or 3 units, a line on a syringe is a big share of the dose, so 2 or 3 mL of water in a 10 mg vial gives you something easier to measure. For the adult study amount of 2 mg, a 10 mg vial mixed with 2 mL of water is 40 units. For any other vial, water or amount, the reconstitution calculator does the same math.

The children's amount goes by body weight. 30 mcg per kg is about 13.6 mcg per pound, so at 150 pounds it is about 2,000 mcg, which is about seven to ten times the vendor range.

Once a night, at bedtime. The children's review gives once daily at bedtime, and the adult study gave one injection each night. Vendors use the same timing.

No set course for adults. The adult study ran 6 weeks. The children's treatment ran 12 months, and data in a few children suggest the effect held out to 36 months.

For planning, 12 weeks at 300 mcg a night is 25.2 mg, which is three 10 mg vials mixed one at a time, since each expires after 28 days. Compare vendors on price per milligram against a total like that, not on the price of one vial.

A mixed vial goes on a 28-day clock in the fridge the day water goes in, however much of it gets used. A 5 mg vial lasts 25 days at 200 mcg a night and 16 days at 300 mcg. A 10 mg vial would last 50 or 33 days, but it expires at 28 days with about 4.4 mg unused at 200 mcg and about 1.6 mg unused at 300 mcg.

That's a buying point. At these amounts a 5 mg vial fits the clock better, and a 10 mg vial only makes sense at a larger amount. At the adult study amount of 2 mg, a 10 mg vial lasts 5 nights.

The pairing people describe is sermorelin with ipamorelin before bed, as two separate injections. No study tests the two together, and each has its own amounts on its own dosage chart. The ipamorelin vs. sermorelin comparison sets them side by side.

CJC-1295 and tesamorelin work through the same receptor as sermorelin, so running either with it is doubling one signal. The CJC-1295 vs. sermorelin comparison covers the difference.

These are reported experiences, not findings from a study of research vials.

Redness, itching or soreness where you injected. Pain at the injection site and facial flushing were the most commonly reported effects in the children's review. People rotate the spot each night.

Puffiness or tingling in the hands. People report it, and some cut the amount or stop.

A headache that doesn't settle. It's reported less often, and people usually stop if it carries on past the first couple of weeks.

The adult study reported no significant side effects over 6 weeks at 2 mg a night, and it's small, so it doesn't rule anything out.