Glutathione dosage chart by form

Glutathione has more human trials than most compounds on this site, and almost all of them are on capsules and liposomal liquid. The injected amounts come from a different place, peptide-information pages and compounding pharmacies, and none of them points to a study. So the chart treats them as separate rows with separate sources, and the numbers don't line up on purpose. Read the source column before you compare one row with another. The glutathione page has the rest, including what the trials found and how the forms differ.

Injectable glutathione is sold as a freeze-dried powder, most often in 1,500 mg vials, with 600 mg the next most common and a few larger and smaller sizes. You mix the powder with bacteriostatic water, which is sterile water with a preservative so one vial can be drawn from more than once. A peptide-information guide mixes a 600 mg vial with 3 mL, which makes 200 mg per mL, and a 1,500 mg vial with 3 mL, which makes 500 mg per mL. The tables below show the units to draw on a U-100 syringe, which holds 100 units in 1 mL, for 1, 2 and 3 mL of water across the amounts in the chart.

Units are math from the chart amounts. For another vial size, water or amount, the reconstitution calculator does the same math. The amounts are big next to most peptides, so a stronger mix (less water) keeps the draw small enough for one syringe.

Two to three times a week. That's the injected pattern a peptide-information guide calls the community range, and a compounding pharmacy's page gives a similar one, one to three times a week, with 100 to 400 mg under the skin and 200 to 600 mg into the muscle. Neither cites a study for it.

Or daily, in smaller amounts. A pharmacy blog describes daily injections, 100 to 300 mg a day for people starting out and 400 to 800 mg a day as a moderate band. It says morning use suits the body's daytime rhythm and evening use fits skin-focused programs, and it cites no source for either. That's a few large injections against many small ones, and nothing compares the two.

No fixed course. The peptide-information guide treats glutathione as an ongoing habit rather than a course with a break, and it says some users run 8 to 12 week injection courses and bridge with NAC or liposomal glutathione between them, which it reads as a way to save money, not a requirement, and it gives no source. The oral trials ran four weeks and six months, and those are the lengths of the studies, not a recommended stop.

By mouth. The capsule trial gave 500 mg once a day for six months, and the liposomal study gave 500 or 1,000 mg once a day for four weeks.

For planning, 200 to 600 mg two to three times a week is 400 to 1,800 mg a week, or 1,600 to 7,200 mg across four weeks. Compare vendors on price per milligram against the total you plan to use, not on the price of one vial.

Glutathione amounts are large, so a vial goes faster than you'd expect from other peptides.

A mixed vial keeps for 28 days in the fridge, and a compounding pharmacy gives the same 28 days for its ready-made solution, counted from the first puncture, with the fridge held between 36 and 46°F. At 200 mg twice a week, a 1,500 mg vial gets through seven doses in 24.5 days, just inside that clock. Anything heavier runs out of vial first, and a 600 mg vial at 600 mg is one dose a time. Compare vendors on price per milligram, since the larger vial isn't always the cheaper one, and a 600 mg vial is the choice if you want to mix less at once.

The trial amounts above are for plain glutathione and liposomal glutathione. S-acetyl glutathione, a chemically modified version some vendors list, hasn't been tested in the trials, so its amounts don't carry over from this chart. The same goes for the precursor route, NAC alone or glycine with NAC, which has its own amounts. People often ask how glutathione sits beside NAD+, and the glutathione vs NAD+ page puts the two side by side, with the NAD+ dosage chart for the other half.

These are effects the pharmacy and information pages list, not findings from a study of research vials.

Pain, redness or swelling where you injected. It's the first reaction the pharmacy page lists, with headache, nausea and diarrhea after it.

Lightheadedness or a shift in digestion. A pharmacy blog lists mild "detox changes", temporary digestive shifts and brief lightheadedness. None of it has been tested, and that wording is the blog's, not ours.

Skin that lightens. The pharmacy page notes glutathione may reduce melanin, the pigment in skin, which is why it's sold for brightening and why it can show up as a change.

Quality matters more than usual here. In 2019 the FDA warned compounding pharmacies not to make injections from supplement-grade glutathione, and in August 2026 two Texas pharmacies recalled glutathione injection vials after their own testing found elevated bacterial endotoxin. A recent third-party certificate of analysis is the thing to look for, and how to read a COA walks through the document.