Editor's Notes
What the research means.
Not summaries — takes. These pieces go beyond what the studies say to ask what they actually mean, what's missing, and what to make of the numbers everyone is citing.
Retatrutide: The Biggest Weight Loss Number We've Seen — and What We Still Don't Know
Retatrutide produced approximately 24% mean body weight reduction in a Phase 2 trial. That number is real. So is how early we are in understanding what this compound actually does.
Read →Tirzepatide (Mounjaro, Zepbound): What the Research Actually Shows
Tirzepatide produced the largest weight reductions ever recorded in a clinical trial. The most important finding, though, isn't the headline number — it's what happens when treatment stops.
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